A March 2021 study by the Institute of Cytology and Genetics, Novosibirsk, Russian Federation found that where there is vital exhaustion - “excessive fatigue, feelings of demoralisation and increased irritability," there is an increased risk of heart attack in men. The study said,
"It is thought to be a response to intractable problems in people's lives, particularly when they are unable to adapt to prolonged exposure to psychological stressors."
"Living alone indicates less social support, which we know from our prior studies is an independent risk factor for myocardial infarction and stroke."
"The relationship of exhaustion with threatening cardiovascular events should be taken into account when assessing risk,”
"Efforts to improve well-being and reduce stress at home and at work can help reduce vital exhaustion. Involvement in community groups is one way to increase social support and become less vulnerable to stress. Together with a healthy lifestyle, these measures should be beneficial for heart health."