Ketogenic diet and multiple sclerosis

A March 2022 study by UVA Health said,

• “The findings …are exciting and serve as a testament to the dedication of our study participants and the resilience of those living with MS.” 

• “People living with MS are highly motivated toward research that studies the link between dietary intake and MS. Our study not only demonstrates the feasibility of dietary changes in MS patients but also the potential benefits that could arise from such interventions. Given the intriguing results of this study, our team is currently looking at how the ketogenic diet impacts the immune profile of MS patients.”

• “Our study provides evidence that a ketogenic diet is safe and beneficial, reducing some symptoms for people with MS, when used over a six-month period,” 

• “Still, more research is needed as there are risks associated with these diets. It is important that people with MS consult with their healthcare provider before making any big changes to their diet, and that they be regularly monitored by a physician and registered dietitian if pursuing a true ketogenic diet.”

Ursolic acid (in fruit peel and herbs) impacts on multiple sclerosis

“Ursolic acid is present in many plants, such as Mirabilis jalapa, as well as in many fruits and herbs used in daily life e.g. apples, basil, bilberries, cranberries, elder flower, peppermint, rosemary, lavender, oregano, thyme, hawthorn, and prunes). Apple peels contain large quantities of ursolic acid and related compounds.” Wikipedia

An April 2020 study by the Sidney Kimmel Medical College at Thomas Jefferson University said,

• "Although the evidence is preliminary - our data is from animal models of disease - it's encouraging to see a compound that both halts and repairs damage in [multiple sclerosis] MS, in the lab."

• "Many experiments have looked at mice in the acute phase, when disease is just starting or at the peak."

• “Instead, we tested whether this compound was effective in chronic disease, once there has already been chronic damage to tissues of central nervous system."

• "It's not a cure, but if we see a similar response in people, it would represent a significant change in quality of life. And most significantly, it's a reversal, which we really haven't seen before with other agents at such a late stage of disease”