An August 2019 study by the University of Texas Medical Branch at Galveston stated,
“Earlier studies discovered that insulin resistance causes dysfunction within the brain's small blood vessels. Since this issue is also present in fibromyalgia, we investigated whether insulin resistance is the missing link in this disorder.”
“We showed that most - if not all - patients with fibromyalgia can be identified by their A1c levels, which reflects average blood sugar levels over the past two to three months."
“Pre-diabetics with slightly elevated A1c values carry a higher risk of developing central (brain) pain, a hallmark of fibromyalgia and other chronic pain disorders."
"Considering the extensive research on fibromyalgia, we were puzzled that prior studies had overlooked this simple connection,"
"The main reason for this oversight is that about half of fibromyalgia patients have A1c values currently considered within the normal range. However, this is the first study to analyze these levels normalized for the person's age, as optimal A1c levels do vary throughout life. Adjustment for the patients' age was critical in highlighting the differences between patients and control subjects."