An August 2024 study by the University of California - San Francisco said,
“Our findings led us straight to the biology of one of the deadliest cancers, pancreatic cancer,”
"Our findings open a point of vulnerability that we can treat with a clinical inhibitor that we already know is safe in humans,”
“We now have firm evidence of one way in which diet might be used alongside pre-existing cancer therapies to precisely eliminate a cancer.”
"Fasting has been part of various cultural and religious practices for centuries, often believed to promote health,"
"Our finding that fasting remodels gene expression provides a potential biological explanation for these benefits."
“The metabolite that the body uses to make energy is also being used as a signal molecule during fasting,”
“To a biochemist, seeing a metabolite act like a signal was the coolest thing.”
“Once we could see how the pathway works, we saw the opportunity to intervene,”
“The field has struggled to firmly link diet with cancer and cancer treatments … But to really connect these things productively, you need to know the mechanism.”
“We expect most cancers to have other vulnerabilities … This is the foundation for a new way to treat cancer with diet and personalized therapies.”