A May 2021 study at The Ohio State University said,

  • "We don't want people to think they can eat everything they want because of this lower BMI association,”

  • "We know that maintaining a healthy weight and having a healthy diet are extremely important to keeping inflammation and oxidative stress down - that's a risk factor that is modifiable, and it's something you can do to help improve your life and prevent neurodegenerative processes as much as possible,” 

  • "If you start to notice rapid weight loss in an older individual, that could actually be a reflection of a potential neurodegenerative disease process."

  • "We're trying to add more and more factors. That is my goal, to one day build a more precise and better model of the different combinations of risk factors," 

  • "Genetic risk is important, but it really explains only a small part of Alzheimer's disease, so we're really interested in looking at other factors that we can control."

  • "We think there's interaction between the genetics and lower BMI, and having both of these risk factors causes more degeneration in certain brain regions to increase the likelihood of developing Alzheimer's disease," 

  • "If you can identify people at higher risk before symptoms manifest, you could implement interventions and prevention techniques to either slow or prevent that progression from happening altogether," she said.

  • "We're finding again and again how important inflammation is in the process,”

  • "Especially in midlife, trying to keep that inflammation down is such an important aspect of maintaining a healthy lifestyle and preventing accelerated aging."