A March 2017 study by the Beckman Research Institute of City of Hope found that,

"Androgens, a type of male sex hormone, promote the growth of prostate cancer cells by binding to and activating the androgen receptor, a protein that is expressed in prostate cells," 

"White button mushrooms appear to suppress the activity of the androgen receptor."

"We found that white button mushrooms contain chemicals that can block the activity of the androgen receptor in mouse models, indicating this fungus can reduce PSA levels,”

"While more research is needed, it's possible that white button mushrooms could one day contribute to the prevention and treatment of prostate cancer."