A July 2019 study by University of Wisconsin School of Medicine found that, “in a late-middle-age population at risk for Alzheimer's disease, physically active individuals experience fewer age-related alterations in biomarkers associated with the disease, as well as memory and cognitive functioning … [showing] evidence that lifestyle habits - in this case regular, moderate exercise - can modify the effect of what is commonly considered a non-modifiable risk factor for Alzheimer's, in this case aging"
https://www.eurekalert.org/pub_releases/2019-08/apa-rem080119.php